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Quantitative analysis of Golgi fragmentation indicates that overexpression of WT ArfGAP1 induces pronounced Golgi fragmentation in ∼85% of cells, whereas phospho-null (3A) ArfGAP1 significantly attenuates Golgi fragmentation (∼43% cells) (Figure 3B)

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Symptoms include severe abdominal pain that radiates to the back, nausea, and vomiting