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These effects are summarized in Table 1 and consist of alterations in lipid metabolism leading to intracellular lipid and cholesterol accumulation [35,36,37,38,39,40,41,42,43,44,45], increased oxidative stress [39,46] and glucose metabolism [43,45], altered cell cycle regulation [44,47,48] and increased intracellular protein recycling [49,50,51]