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The MPTP-induced parkinsonian syndrome in the goldfish is associated with major cell destruction in the forebrain and subtle changes in the optic tectum

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They observed that several lipids (n = 15) changed significantly, including increased levels of triacylglycerols and decreasing levels of phospholipids in the culture media ( Another aspect to consider in vitro metabolomic analysis is the occurrence of hyperosmolarity which is a consequence of a too high concentration of the xenobiotic being assayed