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Melanocortin receptor agonists Cleavage of POMC produces, among other peptides, α-MSH, which activates melanocortin 3 and 4 receptors (Mc3r, Mc4r) to exert catabolic effects [54]

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As reported by Ng et al., Journal of Endocrinology , AOD-9604 does not increase IGF-1 levels, making it safer for long-term use

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