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The 2026 Sports Medicine and JAAOS Global Research and Reviews papers (PMID 41966639, PMID 41490200) place multiple compounds — including this one — into the wider research context of unapproved compounds under active investigation, with attention to both the mechanism findings and the regulatory framing that researchers consulting these reviews should weigh equally

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TB-500 (and Thymosin Beta-4) is listed on the World Anti-Doping Agency's Prohibited List under: For the broader cross-agency picture, including FDA, TGA, WADA, and USADA language, continue with this TB-500 regulatory status guide and compare it with our TB-500 legal status breakdown

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