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Glutax 1000 L-Glutathione Effervescent Tablets, Orange Flavor, 15 Count | N-Acetylcysteine, Vitamin C & Selenium, Antioxidant Support for Skin Glow & Radiance, Sugar-Free Health & Personal Care
The aldose reductase-mediated pathway plays a pivotal role, where hyperglycemia-induced aldose reductase activation generates ROS, leading to p53 phosphorylation (Ser15), mitochondrial Bcl-xL sequestration, and subsequent mitochondrial damage (Pitocco et al., 2013
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