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However, in several studies only a partial improvement but not normalization of the barrier was found on a long-term gluten-free diet (79–81), suggesting either that inadvertent dietary mistakes are made or that a barrier defect is a primary event in the pathophysiology of CeD

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The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men