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Quercetin significantly inhibits tumor angiogenesis, a mechanism involving the suppression of COX-2 and hypoxia-inducible factor-1α expression, 11 and functions by downregulating the expression of VEGF-C and its receptor VEGFR-3 in gastric cancer MGC-803 cells
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The development of new linkers is steadily progressing, further enriching ADC design strategies to enhance their clinical value in the future
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