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They are not derived from controlled human trials, and specific pharmacokinetic figures (bioavailability, half-life, peak timing) are estimates that have not been validated in published human studies

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Studies show cortisone provides meaningful short-term pain reduction in 73–80% of cases, 2 and for acute plantar fasciitis — pain that's been around less than three months — it can be genuinely effective as part of a broader treatment plan