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The use of metformin in a regimen with other antihyperglycemic medications, such as sodium-dependent glucose transporters-2 inhibitors, dipeptidyl peptidase-4 inhibitors, glibenclamide, glucagon-like peptide-1 receptor agonists, is more effective than metformin alone in lowering blood glucose levels [41]
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Hyperpigmentation inside the mouth due to low B12 levels may appear as bluish or dark discoloration
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