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Differently from GSH, which enters the cells directly, SAG is more stable in blood plasma and, once entered into cell cytoplasm, is converted by cytoplasmatic thioesterases to GSH

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Application of the procedure to measure GSH in human blood In a group of 23 healthy subjects, the GSH content in blood was determined by the present micro-method to be 8.54 ± 0.11 nmol/mg Hb, with a standard error of 0.024