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The PCAC recommendation is non-binding – the FDA could still ignore them – but odds are good IMO
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In diabetic periodontitis models, hyperglycemia inhibits autophagic flux through the mTOR-ULK1 pathway, leading to mitochondrial ROS accumulation and promoting Porphyromonas gingivalis-induced NLRP3 inflammasome activation and pyroptosis (140)
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