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Specifically, we highlight three major pathways implicated in ferroptosis: the activation of polyunsaturated fatty acids (PUFAs) and their integration into membrane lipids, the oxidation of these lipids by the labile iron pool (LIP) to generate lipid peroxides, and the impaired function of glutathione peroxidase-4 (GPX4) in preventing lipid peroxide formation [10, 11]
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PACK:Progress - Pack of 2 (40 Tabs)
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