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It remains essential for protecting children from severe TB, including disseminated and meningeal disease, by reducing TB-related mortality (Sadigurschi et al., 2025)
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Immunosuppressive therapy is associated with an overall response rate of 60 to 80% and a 5-year survival rate of 75% in most reports, but event-free survival rates are in the range of 35 to 50% (Bakhshi & Besa, 2023)
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