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Reduced appetite and food intake via central nervous system GLP-1 receptor activation [1]

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Warning: Supplementing with folate, even in some cases of high dietary folate intake, “prevents” or “masks” this folate trap process, but it does not remedy B12 deficiency or homocysteine accumulation (although it is possible that the latter may appear somewhat lower in the analysis than if you were not taking a diet high in folate, as folate is a cofactor that lowers homocysteine