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[DOI] [PubMed] [Google Scholar] 225.Asensio-López MC, Lax A, Pascual-Figal DA, Valdés M, Sánchez-Más J

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The SURMOUNT-4 trial (Aronne 2023, JAMA) showed that adults who stopped tirzepatide after 36 weeks regained an average of 14.0% of body weight over the next 52 weeks, while those who continued tirzepatide lost an additional 5.5% — a 19.4% between-group difference