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In vitro studies using MDCK cells (a model of intestinal epithelial permeability) demonstrated that PLGA nanoparticles significantly enhanced cellular uptake and transport of puerarin across cell monolayers, achieving a permeability coefficient value of 2.83 ± 0.27 × 10 −5 cm/s, which was significantly higher than that observed for free puerarin (0.38 ± 0.07 × 10 −5 cm/s)
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doi: 10.1021/acsami.1c22720 [DOI] [PubMed] [Google Scholar] 179.Ramesh A, Malik V, Ranjani HA, et al
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