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In laboratory research, its activity on skin's structural molecules has been observed at just 1–10 nanomolar — a very low, nontoxic level , where GHK-Cu stimulated both the synthesis and breakdown of collagen and glycosaminoglycans.1 Signaling molecules like this work by fitting a lock, not by flooding the room

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[DOI] [PubMed] [Google Scholar] [156].Renzing J, Hansen S, Lane DP, Oxidative stress is involved in the UV activation of p53, J