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A second cohort of mice including WT, RAMP1 KO, RAMP3 KO, and RAMP1/3 KO genotypes confirmed that both RAMP1 and RAMP3 are individually essential for a full cagrilintide-induced neuronal activation response
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Therefore, GhGPX4 was selected as the candidate gene, and a recombinant protein constructed to investigate its involvement in the ROS metabolic pathway ( Figure 11a )
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