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64.5% treated with cranial irradiation), 6.1% reported the development of a seizure disorder, and seizures occurred more than 5 years after diagnosis in 51% of these patients.[91] An SJLIFE study evaluated the impact of seizure-related factors on neurocognitive, health-related quality of life (HRQOL), and social outcomes in 2,022 childhood cancer survivors (median age, 31.5 years