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In AML17 study of 109 patients, the incidence of hepatotoxicity was 69%, with grade (NCICTC v3.0) 1, 2, 3, and 4 liver injuries occurring in 23%, 23%, 20%, and 5% of patients, respectivelythe first course of treatment with ATO-ATRA (Burnett et al., 2015)

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Moreover, engaging in therapy can be beneficial to mitigate potential psychological distress and manage stress, thereby promoting overall well-being