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For example, a 2016 review found that having a higher level of selenium exposure could offer protection against breast, lung, colon, gastric, esophageal and prostate cancers
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However, when the alkaloids were tested at submicromolar concentration, an increase in apical to basolateral permeability was observed in presence of the P-gp inhibitor, valspodar (PSC833), suggesting P-gp-mediated efflux (Yusof et al., 2019)
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