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Third, further research is needed to optimize dialysis modality-specific effects on eryptosis: while PD patients exhibit higher eryptosis levels than HD patients, potentially due to glucose-based dialysate components, conflicting data on RBC survival across modalities highlight the need for large-scale, longitudinal studies to compare the impact of conventional HD, hemodiafiltration (HDF), and biocompatible PD solutions on eryptosis rates and long-term anemia outcomes