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Using B6 as a cofactor, Hcy can also be converted to cysteine via transsulfuration for use in glutathione synthesis [34] (Figure 1)

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In the vast majority of cases, surgery alone does not cure advanced-stage solid-tumor cancer, because cancer is a systemic disease affecting the entire body, and circulating tumor cells (CTCs) and circulating cancer stem cells (CSCs) are already in other parts of the body