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This research was funded by ANID FONDECYT iniciación 11230112 (LS), Concurso de Investigación con Colaboración Internacional de la Universidad Finis Terrae (LS), ANID FONDECYT regular 1220097 (MM-C)
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R While Gilbert syndrome itself is considered benign, reduced UGT1A1 activity also impairs glucuronidation of drugs (irinotecan toxicity is dramatically increased in UGT1A1*28 homozygotes) and estrogens
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