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Next, the attenuation in calf was confirmed and the capacity of these candidate vaccines to induce immune responses in the natural host was evaluated in the calf model ( Figure 1C )
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various ages in childhood studies) and using different cutoffs for “deficiency.” Similarly, vitamin B 12 was measured as total B 12 in some studies, active B 12 (holotranscobalamin) in others, and folate was not uniformly reported despite its interdependence with B 12
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