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There are three major gene editing platforms: zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and the clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins (CRISPR/Cas) system

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Experimental design models and groups In this study, a detailed overview of the entire experimental process is provided to elucidate the treatment and observation timeline (Fig