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In particular, topiramate may control the flow of glutamate and cysteine through System Xc-, which could impact GSH synthesis and improve the ability of GPX4 to change harmful lipid hydroperoxides into safe lipid alcohols
AZADI 79
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Thus, these comorbid conditions may further exacerbate the proinflammatory endothelial and monocyte phenotypes associated with preexisting G6PD-d, thereby compounding CVD risk 28,29,30
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