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Using neurons obtained from the locus coeruleus of transgenic mice expressing a FLAG-tagged MOR, chronic morphine but not methadone during 6 days was shown to inhibit resensitization and recycling after an acute [Met 5 ]-enkephalin exposure (Quillinan et al., 2011)

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Whereas protein is made from 100 or more amino acids, peptides are smaller chains of around 3-30 amino acids [1]