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The Model of Interstitial Cystitis for Evaluating New Molecular Strategies of Interstitial Regeneration in Humans
Cell Rep Med 2023;4:100942.ArticlePubMedPMC 19
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Final evidence for a causal role of elevated levels of cytosolic or extracellular self-DNA as a driver of systemic inflammation in severe COVID-19 remains to be provided, and it will be difficult to separate the TLR-mediated pro-inflammatory effects of CoV-2 S from pro-inflammatory effects that are – as suggested by the present work – caused by self-DNA release due to CoV-2 S-mediated damage to genomic DNA and the nuclear envelope
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