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Hybrid Harms Feature #2: Whole-Body Distribution Animal biodistribution studies reveal that LNP-encapsulated synthetic mRNA disperses widely, crossing the blood-brain and placental barriers and concentrating in liver, spleen, ovaries, adrenal glands, testes, heart, brain, uterus, spinal cord, thymus, pituitary, eyes, and bone marrow
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Rare but serious events encompass provocation or exacerbation of seizures in susceptible individuals and hypersensitivity reactions ranging from urticaria to anaphylaxis
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