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These include insulin resistance, impaired appetite signaling, and chronic low-grade inflammation, all of which can make weight loss more difficult
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maintenance 400 mg once daily, to be taken at night, alternatively maintenance 400 mg twice daily, to be taken in the morning and at night NSAID-associated ulceration ▶ ▶ BY MOUTH ▶ Adult: 0.8–1.6 g daily in 4 divided doses, dose to be taken 1–1½ hours before meals INTERACTIONS → Appendix 1: H2 receptor antagonists SIDE-EFFECTS ▶ Rare or very rare Anaphylactic reaction
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