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Lip-1 and deferiprone have exhibited consistent neuroprotective effects in preclinical models of glaucoma and DR, while some natural compounds are increasingly recognized for their capacity to modulate the GPX4/Nrf2 axis, thereby suppressing ferroptosis in LECs and Müller cells (75, 125, 126, 128)
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Nat Rev Neurosci (2006) 7(4):295–309
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