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All AuNP types were rapidly cleared from the bloodstream and accumulated exclusively within lysosomes of Kupffer cells and liver sinusoidal endothelial cells, where their metallic cores remained intact with no evidence of degradation or clearance over the 7-week period

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Relevant studies were identified primarily through searches of PubMed, Web of Science, and Scopus, with a focus on publications from approximately 2000 to 2024