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Estrogen modulates the local renin angiotensin system via downregulation of ACE and simultaneous upregulation of ACE2, AT2R and ang (1-7) receptor expression levels [57]
SkinConcern_Main_Pigmentation
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pantoprazole + domperidone 12 hourly for a further seven days and local application of triamcinolone acetonide cream on the ulcers six hourly was also continued for further seven days
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