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A leaky gut allows harmful substances to pass into the bloodstream, which triggers chronic inflammation, leading to more histamine release and poor breakdown
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The most common drug related adverse events reported in adult subjects treated with 2.5-10 g hydroxocobalamin intravenously were reddening of the urine or skin, cutaneous or pustular/papular rash, and an increase in blood pressure (Fortin et al., 2006
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