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3-phosphoglycerate generated from glycolysis in cancer cells is oxidized by PHGDH (phosphoglycerate dehydrogenase) to 3-phosphohydroxypyruvate, a precursor for de novo serine synthesis ( Figure 1 ) ( Conclusion In this review, we delve into the functions and regulation of various glucose transporters and key enzymes catalyzing pivotal steps in glucose metabolism, as well as the impact of metabolites on decidualization ( Figure 1 )

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Soluble His-tagged GpoA protein was purified using nickel affinity chromatography following manufacturer’s instructions (Ni-NTA agarose, Qiagen)