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In a group of 65 female patients with HT, after 10–12 weeks of L-thyroxine treatment and simultaneous restoring euthyroid state, not only was there a statistically significant decrease in the serum levels of TSH, TgAb and TPOAb, a concomitant increase in fT4 serum levels was achieved

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Since these initial observations, propagative activity has been reported in many additional contexts involving different cell types and modes of ferroptosis induction