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In light of the new information obtained here, it can be concluded that acrolein was present under the conditions used, and that after GSH addition, an inactive GSH-acrolein conjugate was formed

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Lipid receptors in the structural components of the airway may be involved in the development of obesity-induced ASM remodeling, with one crucial receptor being free fatty acid receptor 1 (FFAR1), serving as a sensor for medium- and long-chain free fatty acids and expressed on ASM (306, 307)