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Examples of research applications include: Cellular redox investigations Oxidative metabolism research Biochemical signalling studies Antioxidant pathway analysis Comparative molecular investigations Intracellular biochemical modelling Controlled in vitro biochemical studies These applications are intended exclusively for scientific and laboratory investigation

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Upon entering the cytoplasm, glutamine is first processed by glutaminase (GLS) and glutamate dehydrogenase (GLUD) to generate alpha-ketoglutarate (α-KG), which then enters the TCA cycle