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RNAi- MEKK1 -triggered cell death, as evidenced by trypan blue staining, and elevated H 2 O 2 accumulation detected by 3,3′-diaminobenzidine (DAB) staining were also suppressed in let7-1 (Fig

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By contrast, another recent study found no difference in pH gradients across the IM of cristae relative to IBM, suggesting that cristae morphology does not enhance transmembrane energetics, and concluding instead that the driving force for ATP synthesis is promoted by a kinetic coupling mechanism [107] (Figure 3E)