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MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases
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BsAb targeting c-MET and CTLA-4 While PD-1 primarily regulates immune responses in peripheral tissues to prevent tissue damage, cytotoxic T-lymphocyte associated protein 4 (CTLA-4) is critical in controlling T cell activation and proliferation in secondary lymphoid organs, modulating the immune response, and enhancing antitumor immunity
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