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Research has found that mast cells also have the ability to synthesize and store thyroid hormones like T3 and TSH, suggesting that mast cells can modulate thyroid function, and an increase of mast cells has been observed in cases of hypothyroidism
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Here's why that combination is interesting: rapamycin inhibits mTOR, the cellular growth pathway that, when chronically overactivated, drives cellular senescence in follicle stem cell niches
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