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Some studies have reported modest benefits, while others have failed to replicate them [226]

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( Figure 1 ) Figure 1 3 Mechanisms of lipid metabolic changes in DKD 3.1 Metabolic reprogramming (MR) MR refers to the ability of cells to adapt their metabolic processes in response to changing environmental conditions (95) and MR in DKD mainly manifests as renal lipid accumulation (96)

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