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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Stelzig K.E., Canepa-Escaro F., Schiliro M., Berdnikovs S., Prakash Y.S., Chiarella S.E

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In contrast, the lactate concentration in the tumor microenvironment (TME) is significantly elevated, with local concentrations reaching 10–40 mM, which is substantially higher than those observed in normal tissues