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Polyphenols and Oxidative Stress Polyphenols are renowned for their potent antioxidant properties, which play a critical role in mitigating oxidative stress, a key contributor to the pathogenesis of numerous chronic diseases, including neurodegenerative disorders, cardiovascular diseases, and cancer (Saeed et al

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Hemin enhances CD8 + T cell IFN-γ secretion, and elevated IFN-γ synergizes with hemin to induce tumor cell ferroptosis [90]