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Interplay of IEC Death and Immune Dysregulation in Barrier Disruption During the active phase of IBD, an upregulation of programmed cell death within the intestine significantly compromises the integrity of the intestinal barrier

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Rats were housed in a humidity- (50 ± 5%) and temperature-controlled (23 ± 2℃) room, under a 12/12 h light (200 lux)/dark cycle, with rodent standard chow and water available ad libitum