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[9] Intracellular A Juxtamembrane segment that contains: a serine residue (Ser 985), which inhibits the receptor kinase activity upon phosphorylation [10] a tyrosine (Tyr 1003), which is responsible for MET polyubiquitination, endocytosis, and degradation upon interaction with the ubiquitin ligase CBL [11] Tyrosine kinase domain, which mediates MET biological activity
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