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2 are some of the common (glutathione, Cys, Coenzyme A, homocysteine and lipoic acid) and organism-specific LMW thiols found in such species as Actinomycetes (mycothiol), Firmicutes (bacillithiol), halobacteria and lactic acid bacteria (γ-Glu-Cys), trypanosomes (trypanothione), fungi and mycobacteria (ergothioneine) and methanogenic archaea (Coenzyme M and Coenzyme B) [6–8]
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In addition, copper increased glutathione oxidation through oxidative stress and reduced the degree of glutathione conjugation [40], resulting in the oxidation of catecholamines in vivo and subsequent cardiotoxicity