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The most commonly acknowledged serotonin presentation can be from the enterochromaffin cells out of tissues into the blood, secreted luminally and basolaterally increased serotonin uptake by circulating platelets and activation after stimulation, toward the increased stimulation of myenteric and gastrointestinal motility [187]

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People taking semaglutide for weight loss may experience: Dizziness Fatigue Gastrointestinal issues, such as diarrhea, constipation and gassiness Headache Stomach issues, including nausea, vomiting, pain or distension (bloat) Gastrointestinal issues are the most common complaint among people just starting semaglutide